prevalence of keratoconus in patients with mitral valve prolapse

purpose: to determine the prevalence of keratoconus (kcn) in patients with mitral valve prolapse (mvp). methods: this descriptive study was conducted on patients with mvp at shahid rajaei hospital during 2003-2004. corneal topography was performed in 392 subjects with absolute mitral valve prolapse based on perloff’s major criteria. orbscan was carried out in suspected kcn cases. results: patient consisted of 247 men (63%) and 145 women (37%) with mean age of 37.27 ± 11.29 years. the diagnosis of two topographically kcn suspect patients was not confirmed with orbscan. positive family history of keratoconus in first-degree relatives was found in three patients. no cases of keratoconus were found. conclusion: this study suggests that the prevalence of kcn in patient’s with mvp could be less than previously reported. a large multicenter study is needed to detect the association of these disorders. genetic studies are suggested.